General Cell Lines and Cell Cultures
Eurofins Discoverx ChemiScreen CRTH2/DP2 Prostanoid Receptor Membrane Preparation, 1 vial. (HTS031M)
The ChemiScreen CRTH2/DP2 Prostanoid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of PTGDR2 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach or to screen for GPCR activity using GTPγS assays. Increased binding affinities or GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Biochain Institute Inc Matched Pair - DNA - Human Primary Tumor and Normal Tissue: Lung, 2x10 ug/PK
BioChain's human DNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of DNA prepared from primary tumor and its adjacent normal tissue; PM consists of DNA prepared from primary tumor and corresponding ponding metastatic tumor. Genomic DNA in each pair is prepared from the same donor. This product line is designed foridentifying tumor-specific genes and tumor metastatic genes.
Eurofins Discoverx PrecisION hCav3.2 Recombinant Stable Cell Line, 2 vials. (CYL3075)
The PrecisION hCav3.2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Cav3.2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Cav3.2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC Salmonella enterica; subsp. enterica; serovar Bispebjerg
Bacteriophage host. Used as a control strain for the detection of Salmonella and in the examination of dairy products.
Cayman Chemical GPR120 Compound A 10mg
An orally available, selective agonist of GPR120 (EC50 = ~0.35 µM); exerts anti-inflammatory effects on macrophages in vitro and improves glucose tolerance, decreases hyperinsulinemia, increases insulin sensitivity, and decreases hepatic steatosis when included at 30 mg/kg body weight in a high-fat diet fed to obese mice
Lonza Walkersville Mouse C57 Brain Striatum Neuro
Ready-to-use Clonetics Mouse C57 Brain Striatum Neurons (M-CP-302) are isolated from mouse C57 black brain (E14 15) These are sold as cell suspensions of high quality primary embryonic brain neuronal cells (including glia) prepared by standardized methods and are ready for immediate culture Each vial of striatum cells contains approximately 4 million viable cells This will seed into 6 or more wells of a 24-well plate and 30 or more wells of a 96-well plate using the recommended plating densities and medium After approximately 4 days in culture the cells will form a neurite network and by the 7th day debris will be minimal Recommended medium PNGM BulletKit (CC-4461)
ATCC Giardia intestinalis; Portland-1
Giardia intestinalis strain Portland-1 was isolated in Portland, Oregon. This parasitic protozoan has applications in food and waterborne pathogen research.
Biochain Institute Inc Frozen Tissue Section - Alzheimer's Disease: Brain: Medulla oblongata, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Frozen Tissue Section - hypertension: Artery, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Frozen Tissue Section - hypertension: Vein, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
ATCC Aspergillus clavatus; Kral; genomic DNA
Genomic DNA isolated from Aspergillus clavatus QM 1276. This fungal strain is also available as ATCC Catalog No.: 1007™.
Eurofins Discoverx PathHunter OPRM1 Total GPCR Internalization U2OS Cell Line, 2 vials. (93-0745C3)
The PathHunter OPRM1 Total GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of OPRM1 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged OPRM1 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the OPRM1 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 mGCGR β-Arrestin Cell Line, 2 vials. (93-0575C2)
The PathHunter mGCGR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. glucagon) based activation of mGCGR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGCGR and EA-tagged β-Arrestin-2. Activation of mGCGR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.